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[Symptomatic left ventricular dysfunction and Behçet disease. Report of 2 cases]
A Scheuble1, O Belliard, S Robinet
1Hôpital Saint-Antoine, service de cardiologie, 184, rue du Faubourg Saint-Antoine, 75571 Paris.
Archives Des Maladies Du Coeur Et Des Vaisseaux
|November 25, 2003
Summary
Behçet
Area of Science:
- Cardiology
- Rheumatology
- Pathology
Background:
- Behçet's disease, a systemic vasculitis, can affect cardiac structures in 1-6% of cases.
- Cardiac involvement includes pericardial, coronary, and myocardial disease.
- Left ventricular dysfunction, presenting as dilated cardiomyopathy, is a potential complication.
Observation:
- Two cases of Behçet's disease with symptomatic left ventricular dysfunction are presented.
- One case demonstrated dilated cardiomyopathy with normal coronary arteries, suggesting inflammatory myocarditis.
- Echocardiographic studies indicate underdiagnosis of myocardial disease in Behçet's patients.
Findings:
- Left ventricular dysfunction can occur in Behçet's disease, independent of coronary artery disease.
- Myocardial inflammation (myocarditis) is a potential cause of cardiac dysfunction.
- 20-35% of asymptomatic Behçet's patients exhibit left ventricular diastolic dysfunction.
Implications:
- Early detection of myocardial involvement in Behçet's disease is crucial.
- Assessing left ventricular diastolic function aids in timely diagnosis of cardiac complications.
- This highlights the importance of comprehensive cardiac evaluation in Behçet's disease management.