Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene Flow02:39

Gene Flow

37.5K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
37.5K
Gene Families01:57

Gene Families

9.8K
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
9.8K
Gene Therapy00:59

Gene Therapy

27.4K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.4K
What is Gene Expression?01:42

What is Gene Expression?

194.9K
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
194.9K
Gene Conversion02:08

Gene Conversion

10.6K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
10.6K
Organization of Genes02:07

Organization of Genes

73.2K
Overview
73.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical characteristic and management of haemophilia patients in Malaysia: A single centre experience.

The Medical journal of Malaysia·2024
Same author

Matrix Matters: Assessment of Commutability among BK Virus Assays and Standards.

Journal of clinical microbiology·2022
Same author

Three-dimensional pharyngeal airway changes in dento-skeletal class II patients after two-jaw orthognathic surgery with segmentation - a pilot study.

Journal of stomatology, oral and maxillofacial surgery·2018
Same author

Letter to the editor on the article "Impact on the upper airway space of different types of orthognathic surgery for the correction of skeletal class III malocclusion: A systematic review and meta-analysis".

International journal of surgery (London, England)·2017
Same author

Novel TKI-resistant BCR-ABL1 gatekeeper residue mutations retain in vitro sensitivity to axitinib.

Leukemia·2015
Same author

Carotid intima media thickness and high sensitivity C-reactive protein as markers of cardiovascular risk in a malaysian population.

The Medical journal of Malaysia·2014
Same journal

"Gazing into the crystal ball of mortality prediction in conservative kidney care": Correspondence.

Annals of the Academy of Medicine, Singapore·2026
Same journal

Vascular stiffness and sepsis mortality: A promising signal in search of clinical relevance.

Annals of the Academy of Medicine, Singapore·2026
Same journal

Transcatheter aortic valve implantation for severe aortic regurgitation with Trilogy system: Initial Southeast Asia experience.

Annals of the Academy of Medicine, Singapore·2026
Same journal

Singapore expert consensus on optimising lipid-lowering strategies in acute coronary syndrome: A modified Delphi study.

Annals of the Academy of Medicine, Singapore·2026
Same journal

Association of estimated pulse wave velocity with 28-day mortality in sepsis: A MIMIC-IV study.

Annals of the Academy of Medicine, Singapore·2026
Same journal

Prognostic value of the monocyte-to-albumin ratio in nasopharyngeal carcinoma: A retrospective cohort study.

Annals of the Academy of Medicine, Singapore·2026
See all related articles

Related Experiment Video

Updated: Jan 22, 2026

Author Spotlight: Advancing Gene Editing in Bamboo Leaves for Sustainable Plastic Alternatives
06:57

Author Spotlight: Advancing Gene Editing in Bamboo Leaves for Sustainable Plastic Alternatives

Published on: August 18, 2023

2.2K

From genesis to genes.

S K Tan1

  • 1Singapore Health Services, Department of Orthopaedic Surgery, Singapore General Hospital.

Annals of the Academy of Medicine, Singapore
|November 25, 2003
PubMed
Summary
This summary is machine-generated.

Modern medicine evolved from ancient practices, with scientific foundations established in the 19th century. Advances in genomics, stem cells, and gene therapy offer new hope for treating genetic diseases and age-related conditions.

More Related Videos

Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
10:34

Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells

Published on: April 14, 2010

16.0K
Using the Gene Pulser MXcell Electroporation System to Transfect Primary Cells with High Efficiency
12:55

Using the Gene Pulser MXcell Electroporation System to Transfect Primary Cells with High Efficiency

Published on: January 6, 2010

24.7K

Related Experiment Videos

Last Updated: Jan 22, 2026

Author Spotlight: Advancing Gene Editing in Bamboo Leaves for Sustainable Plastic Alternatives
06:57

Author Spotlight: Advancing Gene Editing in Bamboo Leaves for Sustainable Plastic Alternatives

Published on: August 18, 2023

2.2K
Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
10:34

Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells

Published on: April 14, 2010

16.0K
Using the Gene Pulser MXcell Electroporation System to Transfect Primary Cells with High Efficiency
12:55

Using the Gene Pulser MXcell Electroporation System to Transfect Primary Cells with High Efficiency

Published on: January 6, 2010

24.7K

Area of Science:

  • Medical History
  • Genetics
  • Biotechnology

Background:

  • Humanity has long sought to understand and treat diseases, with early efforts predating scientific methodology.
  • The discovery of microorganisms in the 19th century revolutionized medicine by identifying disease causation.
  • 20th-century advancements significantly improved understanding of human physiology and therapeutic interventions.

Observation:

  • The completion of the Human Genome Project marked a milestone in life sciences.
  • The 21st century has witnessed rapid progress in stem cell technology and gene therapy.
  • There is a growing understanding of illnesses linked to genetic defects and abnormalities.

Findings:

  • The exponential increase in identified genetic disorders highlights the importance of genomic research.
  • New therapeutic strategies are emerging for conditions previously considered intractable.
  • Advances enable more effective prevention and treatment of numerous diseases.

Implications:

  • Future medical treatments will increasingly leverage genetic insights and biotechnological tools.
  • There is significant potential for combating age-related diseases, including degenerative conditions and cancers.
  • Personalized medicine approaches are likely to become more prevalent, tailored to individual genetic profiles.