Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Colorectal malignancies in HIV-positive patients.

José F Yegüez1, Sergio A Martinez, Dana R Sands

  • 1Division of Colon and Rectal Surgery, Department of Surgery, University of Miami-School of Medicine/Jackson Memorial Medical Center, Miami, Florida 33136, USA.

The American Surgeon
|November 25, 2003
PubMed
Summary

Colorectal cancer (CRC) in HIV/AIDS patients is aggressive, with a dismal survival rate. Early diagnosis and further research into antiretroviral therapy

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automated assessment of laparoscopic pattern cutting skills using computer vision and deep learning.

Surgery·2025
Same author

Examination Scores but not Clinical Performance Correlate With Duration of Preclinical Didactic Time: A Synchronous Comparison of Second- Versus Third-Year Medical Students on the Surgery Clerkship.

Journal of surgical education·2023
Same author

Effects of Recorded versus Live Teleconference Didactic Lectures on Medical Student Performance in the Surgery Clerkship.

Journal of surgical education·2022
Same author

When is transanal endoscopic surgery appropriate?

Surgical oncology·2022
Same author

Implementation of a Surgical Problem-Based Learning Curriculum: A One-Year Single-Center Experience.

The American surgeon·2022
Same author

Comparison of procedural outcomes between morning and afternoon colonoscopies performed by colorectal surgeons.

Surgical endoscopy·2022

Area of Science:

  • Oncology
  • Infectious Diseases
  • Gastroenterology

Background:

  • HIV/AIDS patients are living longer due to effective medications.
  • This has led to an increase in AIDS-defining malignancies.
  • Colorectal malignancies are increasingly recognized in this population.

Purpose of the Study:

  • To review the occurrence and clinical course of colorectal malignancies in HIV-infected/AIDS patients.
  • To analyze the types of colorectal neoplasms and their survival outcomes.
  • To identify potential associations between HIV, immunosuppression, and colorectal cancer.

Main Methods:

  • Retrospective review of HIV/AIDS patients with colorectal malignant tumors.
  • Inclusion criteria: adult, HIV-positive (ELISA and Western blot), with colon or rectal cancer.

Related Experiment Videos

  • Exclusion criteria: anal malignancies.

    • Main Results:

    • Twelve patients identified: 6 adenocarcinomas (ACA), 5 non-Hodgkin lymphomas (NHL), 1 small-cell carcinoma.
    • Median age 41; intravenous drug abuse was the main HIV risk factor.
    • Five of six ACA patients had metastatic disease at diagnosis; overall survival averaged 20 months (NHL: 29 months, CR-ACA: 12 months).
    • Seven patients underwent surgery, with 85.7% experiencing postoperative complications (primarily wound infection).

    Conclusions:

    • Colorectal cancer in HIV/AIDS patients is aggressive, often diagnosed at advanced stages.
    • Tumors may be linked to HIV-induced immunosuppression and direct HIV effects on colonic epithelium.
    • A high index of suspicion is crucial for chronic abdominal complaints in this group.
    • Further evaluation of antiretroviral therapy's impact on survival is warranted.