Treatment of bleeding in severe hemorrhagic pancreatitis with recombinant factor VIIa

Rob Schuster1, Sarah J Lee, Donald Rink

  • 1Department of Surgery, Santa Barbara Cottage Hospital, Santa Barbara, California 93102, USA.

The American Surgeon
|November 25, 2003
PubMed

Recombinant factor VIIa (rFVIIa) has been used to treat bleeding complications in patients with hemophilia. It acts at the site of vessel injury, forming a complex with tissue factor to activate the clotting cascade. Recent reports have shown rFVIIa may be a useful hemostatic agent in patients after obstetrical, urologic, trauma, or transplant procedures. We report the first documented case of bleeding from hemorrhage pancreatitis treated with rFVIIa.

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