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Published on: July 18, 2014
The clinical course of acquired complete heart block in children with acute myocarditis
A S Batra1, D Epstein, M J Silka
1Division of Cardiology, Riley Children's Hospital, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Insights
Myocarditis in children can cause advanced atrioventricular (AV) block. Most young patients recover AV conduction within a week, but some require permanent pacemakers or face mortality.
Area of Science:
- Pediatric Cardiology
- Electrophysiology
- Pediatric Infectious Diseases
Background:
- Myocarditis, an inflammation of the heart muscle, can lead to serious cardiac complications in children.
- Advanced atrioventricular (AV) block is a critical complication that affects cardiac conduction.
- Understanding the prognosis of AV block in pediatric myocarditis is crucial for clinical management.
Observation:
- A case of biopsy-proven myocarditis in a 7-year-old presented with advanced AV block.
- A literature review identified 40 pediatric patients (age < 20 years) with myocarditis and AV block.
- The study analyzed outcomes including recovery of AV conduction, need for pacing, and mortality.
Findings:
- A significant majority of pediatric patients (67%) with myocarditis-associated AV block experienced recovery of AV conduction within 7 days.
- Persistent AV block requiring permanent pacemaker implantation was observed in 28% of cases.
- Mortality occurred in 5% of the studied pediatric population.
Implications:
- Early identification and monitoring of AV block in pediatric myocarditis are essential.
- The findings suggest a favorable prognosis for AV conduction recovery in most children.
- A subset of patients will require long-term cardiac pacing, highlighting the need for careful follow-up.
Abstract:
A case of biopsy-proven myocarditis in a 7-year-old complicated by advanced atrioventricular (AV) block prompted a review of the medical literature to determine the prognosis for recovery of AV conduction or need for pacemaker implantation. A total of 40 patients younger than 20 years of age were identified, with return of AV conduction within 7 days in 27 patients (67%), permanent pacing in 11 patients (28%) with persistent AV block, and death in 2 patients (5%).
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