The clinical course of acquired complete heart block in children with acute myocarditis

A S Batra1, D Epstein, M J Silka

  • 1Division of Cardiology, Riley Children's Hospital, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Pediatric Cardiology
|November 25, 2003
PubMed

Insights

Myocarditis in children can cause advanced atrioventricular (AV) block. Most young patients recover AV conduction within a week, but some require permanent pacemakers or face mortality.

Area of Science:

  • Pediatric Cardiology
  • Electrophysiology
  • Pediatric Infectious Diseases

Background:

  • Myocarditis, an inflammation of the heart muscle, can lead to serious cardiac complications in children.
  • Advanced atrioventricular (AV) block is a critical complication that affects cardiac conduction.
  • Understanding the prognosis of AV block in pediatric myocarditis is crucial for clinical management.

Observation:

  • A case of biopsy-proven myocarditis in a 7-year-old presented with advanced AV block.
  • A literature review identified 40 pediatric patients (age < 20 years) with myocarditis and AV block.
  • The study analyzed outcomes including recovery of AV conduction, need for pacing, and mortality.

Findings:

  • A significant majority of pediatric patients (67%) with myocarditis-associated AV block experienced recovery of AV conduction within 7 days.
  • Persistent AV block requiring permanent pacemaker implantation was observed in 28% of cases.
  • Mortality occurred in 5% of the studied pediatric population.

Implications:

  • Early identification and monitoring of AV block in pediatric myocarditis are essential.
  • The findings suggest a favorable prognosis for AV conduction recovery in most children.
  • A subset of patients will require long-term cardiac pacing, highlighting the need for careful follow-up.

Related Concept Videos

Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...