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Cross-reactivity induced by Anisakis simplex and Toxocara canis in mice
M J Perteguer1, C Aguila, S Fenoy
1Departamento de Parasitología, Facultad de Farmacia, Universidad Complutense, Madrid, Spain.
Abstract:
The aim of this study was to verify whether cross-reactivity appeared between Toxocara canis and Anisakis simplex in an experimental rodent model. No cross-reactions were detected using sera from mice infected with T. canis eggs. When responses obtained against T. canis ES antigen using sera from BALB/c and C57BL/10 mice infected with T. canis eggs were compared with those obtained by testing sera from mice infected with one A. simplex L3, an increase in cross-reactions was observed using the C57BL/10 strain.

