Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mate Choice01:20

Mate Choice

Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
Understanding Species and Reproductive Barriers01:17

Understanding Species and Reproductive Barriers

A species is a group of organisms that interbreed and produce fertile offspring. Typically, individuals of the same species appear similar and share common characteristics due to their highly similar genomes. However, not all organisms that look alike are members of the same species. Various mechanisms keep most species discrete. While some mechanisms prevent reproductive behavior and fertilization (pre-zygotic isolation), others prevent the production of fertile offspring after mating has...
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Dosage Compensation02:50

Dosage Compensation

In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will have...
Development of the Sexual Organs in the Embryo and Fetus01:15

Development of the Sexual Organs in the Embryo and Fetus

Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal iron deficiency causes male-to-female sex reversal in mouse embryos.

Nature·2025
Same author

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

eLife·2023
Same author

Author Correction: Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects.

Nature communications·2023
Same author

Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects.

Nature communications·2023
Same author

Somatic FGFR2 is Required for Germ Cell Maintenance in the Mouse Ovary.

Endocrinology·2023
Same author

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer-Rokitansky-Küster-Hauser syndrome.

Human molecular genetics·2022

Related Experiment Video

Updated: Jul 11, 2026

Measuring and Altering Mating Drive in Male Drosophila melanogaster
07:02

Measuring and Altering Mating Drive in Male Drosophila melanogaster

Published on: February 15, 2017

Developmental biology: gender benders

Peter Koopman

    Nature
    |November 25, 2003
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Dissection of Larval Zebrafish Gonadal Tissue
    10:43

    Dissection of Larval Zebrafish Gonadal Tissue

    Published on: April 26, 2017

    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish
    09:17

    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish

    Published on: July 22, 2025

    Related Experiment Videos

    Last Updated: Jul 11, 2026

    Measuring and Altering Mating Drive in Male Drosophila melanogaster
    07:02

    Measuring and Altering Mating Drive in Male Drosophila melanogaster

    Published on: February 15, 2017

    Dissection of Larval Zebrafish Gonadal Tissue
    10:43

    Dissection of Larval Zebrafish Gonadal Tissue

    Published on: April 26, 2017

    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish
    09:17

    Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish

    Published on: July 22, 2025