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Longitudinal Intravital Imaging of Brain Tumor Cell Behavior in Response to an Invasive Surgical Biopsy
Published on: May 3, 2019
Neuroendoscopic biopsy for intraventricular tumors
T Yurtseven1, Y Erşahin, E Demirtaş
1Division of Pediatric Neurosurgery, Department of Neurosurgery, Ege University Faculty of Medicine, Karşiyaka, Izmir 35602, Turkey.
Minimally Invasive Neurosurgery : MIN
|November 25, 2003
Summary
Neuroendoscopic tumor biopsy offers a minimally invasive approach for managing intraventricular tumors, enabling simultaneous treatment of hydrocephalus and obtaining crucial diagnostic samples.
Area of Science:
- Neurosurgery
- Oncology
- Minimally Invasive Procedures
Background:
- Intraventricular tumors present complex management challenges.
- Traditional open surgery carries significant risks.
- Neuroendoscopy offers a less invasive alternative.
Purpose of the Study:
- To evaluate the efficacy and safety of neuroendoscopic tumor biopsy.
- To assess the utility of concurrent endoscopic procedures.
- To determine the diagnostic yield of cerebrospinal fluid (CSF) analysis.
Main Methods:
- Retrospective analysis of 18 patients undergoing neuroendoscopic tumor biopsy.
- Procedures performed under general anesthesia using rigid neuroendoscopes.
- Collection of CSF for cytology and tumor markers; biopsy forceps used for tissue acquisition.
Main Results:
- Tumor locations varied, including pineal, hypothalamic, and ventricular regions.
- Pathological diagnoses included various astrocytomas, germinomas, and other rare lesions.
- Concurrent third ventriculostomy was performed in pineal tumor cases.
Conclusions:
- Neuroendoscopic tumor biopsy is a safe and effective minimally invasive technique.
- It allows for simultaneous management of hydrocephalus and definitive tissue diagnosis.
- Neuroendoscopy should be considered for selected intraventricular tumor cases.
