Neuronal stem cells biology and plasticity
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Updated: Aug 30, 2026

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain
Published on: November 18, 2013
Vincent F La Russa1, Debasis Mondal, Alan Miller
1Bone Marrow Transplant Laboratory, Tulane Cancer Center, 1430 Tulane Avenue, SL-34, New Orleans, LA 70112, USA. vlaruss@tulane.edu
Abstract:
Recent studies have suggested that stem cells are able to cross primordial tissue barriers. Their ability to respond to unrelated microenvironmental signals strongly suggest that they have greater potential than previously imagined especially for their future clinical use for the regeneration of tissues or even perhaps organ systems. In particular there is an intriguing reciprocal relationship between the hematopoietic and neuronal stem cell systems. Both stem cell pools appear to respond to microenvironmental signals that are not developmental related. These intriguing observations have led to a number of studies that have attempted to explore this apparent phenomenon of plasticity associated with both hematopoietic and neuronal stem cell populations.
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