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Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
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Published on: June 9, 2018

Oral involvement in a case of AA amyloidosis

A Koloktronis1, I Chatzigiannis, N Paloukidou

  • 1Department of Oral Medicine/Pathology, Dental School of Aristotle University of Thessaloniki, Thessaloniki, Greece. kdeod@cieel.gr

Oral Diseases
|November 25, 2003
PubMed

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Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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