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Acute central and peripheral demyelination associated with Mycoplasma pneumoniae
Maw J Tan1, Arup K Chattophadyay, Paul D Griffiths
1Sheffield Children's Hospital, Western Bank, UK.
Pediatric Neurology
|November 25, 2003
Abstract:
A 7-year-old female presented with Mycoplasma pneumoniae pneumonitis and a progressive ascending limb paralysis. She developed severe respiratory distress, requiring ventilation, and became apparently unresponsive with fixed dilated pupils. Peripheral nerves were inexcitable in nerve-conduction studies. Magnetic resonance imaging of the brain revealed evidence of extensive demyelination. Anti-GM1 immunoglobulin M antibody titers were raised. She improved after a second course of intravenous immunoglobulin and eventually made a full recovery.