Brainstem cranial-nerve lesions in an infant with hypoxic cerebral injury

Recent studies have revealed that the brainstem is characteristically involved in hypoxic encephalopathy in infants. However, few reports have described clinical and cranial magnetic resonance findings in detail because most patients with brainstem lesions die during delivery or soon afterward. Reported here is a patient who manifested selective brainstem injury caused by perinatal hypoxic cerebral injury and exhibited palsy of the lower-brainstem cranial nerves. Magnetic resonance imaging was used to demonstrate lesions of brainstem cranial nerves, which were consistent with symptoms of brainstem dysfunction.