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The mutagenic potentiator effect of chlorophyllin by the HGPRT assay

Priscilla Davidson Negraes1, Berenice Quinzani Jordão, Veronica Elisa Pimenta Vicentini

  • 1Universidade Estadual de Londrina, Departamento de Biologia Geral, Campus Universitario CP 6001, Laboratório de Mutagênese in vitro, Parana 86051 990, Brazil.

Toxicology in Vitro : an International Journal Published in Association with BIBRA
|November 25, 2003
PubMed

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Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...