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Updated: Aug 30, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Non-convulsive status epilepticus associated with tiagabine therapy in children
Angeliki Skardoutsou1, Konstantinos A Voudris, Eleni A Vagiakou
1Second Department of Paediatrics-University of Athens, P & A Kyriakou Children's Hospital, Athens, Greece.
Abstract:
A case of a 7-year-old male with epilepsy who developed non-convulsive status epilepticus (NCSE) with electroclinical features consistent with those of atypical absence seizures after adjunctive antiepileptic therapy of tiagabine (TGB) is reported. The patient had frequent generalised and rare partial seizures with generalised epileptic discharges on prior electroencephalogram (EEG) recordings. NCSE was developed when rapid dosage increase and high dose of TGB was given. This case emphasises the need for close monitoring of children with epilepsy taking TGB for exacerbation of seizures or development of NCSE.
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