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Published on: January 26, 2019
Snoring, daytime sleepiness and stroke: a case-control study of first-ever stroke
D P Davies1, H Rodgers, D Walshaw
1Department of Respiratory Medicine, Freeman Hospital, Newcastle upon Tyne, UK.
Journal of Sleep Research
|November 25, 2003
Summary
Snoring alone is not significantly linked to stroke risk. However, increased daytime sleepiness is a strong indicator, suggesting sleep disorders like obstructive sleep apnoea may be a factor in stroke.
Area of Science:
- Neurology
- Sleep Medicine
- Epidemiology
Background:
- Previous studies suggest a link between snoring and stroke.
- The role of confounding factors and obstructive sleep apnoea (OSA) remains unclear.
Purpose of the Study:
- To investigate the independent association of snoring and daytime sleepiness with first-ever stroke.
- To identify stroke risk factors, including sleep-related variables.
Main Methods:
- A case-control study involving 181 first-ever stroke patients and matched community controls.
- Structured interviews were used to collect data on snoring, daytime sleepiness, and stroke risk factors.
- Multiple logistic regression analysis was employed.
Main Results:
- Snoring alone showed no statistically significant association with stroke (OR 1.44, 95% CI 0.88-2.41).
- Daytime sleepiness was significantly associated with stroke (OR 3.07, 95% CI 1.65-6.08).
- Hypertension, smoking, regular alcohol consumption (negative association), and higher Epworth sleepiness scores were independent stroke predictors.
Conclusions:
- The association between simple snoring and stroke may be due to uncontrolled confounding variables.
- Greater pre-stroke sleepiness is associated with stroke, with OSA as a potential underlying cause.
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