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Relationship between growth and feeding in infancy and body mass index at the age of 6 years
I Gunnarsdottir1, I Thorsdottir
1Unit for Nutrition Research, Landspitali-University Hospital & Department of Food Science, University of Iceland, Reykjavik, Iceland. ingigun@landspitali.is
Insights
Rapid infant growth and high protein intake in boys are linked to higher body mass index (BMI) at age six. These factors may contribute to childhood obesity, highlighting early life influences.
Area of Science:
- Pediatric Nutrition
- Childhood Obesity Research
- Growth and Development Studies
Background:
- Childhood obesity is a growing public health concern.
- Early life factors significantly influence long-term health outcomes.
- Understanding infant growth patterns is crucial for predicting later obesity risk.
Purpose of the Study:
- To investigate the association between infant size and growth metrics and body mass index (BMI) at six years of age.
- To identify potential nutritional contributors to childhood obesity during infancy.
Main Methods:
- A longitudinal observational study followed 90 healthy, full-term infants from birth to six years.
- Infant weight and height were measured periodically, with monthly food records analyzed for nutrient intake.
- Body mass index (BMI) at age six was the primary outcome measure.
Main Results:
- Greater weight gain from birth to 12 months correlated positively with BMI at age six in both boys and girls.
- Boys with higher protein intake between 9-12 months exhibited significantly higher BMI at age six.
- Combined, infant weight gain and protein intake explained 50% of BMI variance in six-year-old boys.
Conclusions:
- Rapid infant growth in the first year is associated with increased BMI at age six.
- High protein intake during infancy may be an additional risk factor for childhood obesity in boys.
- Early life growth and nutrition play a critical role in the development of childhood obesity.
Objective:
To assess the relationship between size and growth measurements in infancy to body mass index (BMI) at 6 y.
Design:
A longitudinal observation study on randomly chosen infants' growth and consumption in infancy. Follow-up until the age of 6 y.
Subjects:
A total of 90 children who were born healthy and full-term.
Measurements:
Weight and height were measured at maternity wards and healthcare centers in Iceland throughout infancy and at 6 y. Food records were made every month during infancy. At 2, 4, 6, 9 and 12 months, food was weighed to calculate food and nutrient intake.
Results:
Weight gain from birth to 12 months as a ratio of birth weight was positively related to BMI at the age of 6 y in both genders (B=2.9+/-1.0, P=0.008, and B=2.0+/-0.9, P=0.032 for boys and girls, respectively). Boys in the highest quartile of protein intake (E%) at the age of 9-12 months had significantly higher BMI (17.8+/-2.4 kg/m(2)) at 6 y than the lowest (15.6+/-1.0 kg/m(2), P=0.039) and the second lowest (15.3+/-0.8 kg/m(2), P=0.01) quartile. Energy intake was not different between groups. Together, weight gain at 0-12 months and protein intake at 9-12 months explained 50% of the variance in BMI among 6-y-old boys.
Conclusion:
Rapid growth during the first year of life is associated with increased BMI at the age of 6 y in both genders. In boys, high intake of protein in infancy could also contribute to childhood obesity.
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