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Updated: Aug 17, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
[Pregnancy during nephropathy]
D Cusi1, M V Taglietti, A Liccardo
1Cattedra e Scuola di Specializzazione in Nefrologia, Universita' degli Studi di Milano, Italy. cusi@unimi.it
Abstract:
We illustrate two cases of pregnancy complicated by previously onset chronic nephropathy. In spite of two completely different pathogenetic mechanisms for chronic renal insufficiency (IgA nephropathy in one case and vescico-ureteral reflux in the other), renal function at the beginning of the pregnancy was similar and only partially impaired. In either case the pregnancy lowered by 50% the residual glomerular filtration rate. Only minimum recovery was observed during several months of follow-up.
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