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Grape anaphylaxis.

M F Caiaffa¹, A Tursi, L Macchia

¹Medical Faculty, University of Foggia, Italy.

Journal of Investigational Allergology & Clinical Immunology

|November 26, 2003

Summary

This summary is machine-generated.

Grape allergy is rare but can cause severe anaphylaxis. Diagnosis requires prick-by-prick testing with fresh grapes, as commercial extracts may be unreliable.

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Area of Science:

Allergy and Immunology
Food Science

Background:

Grape allergy (Vitis vinifera) is uncommon globally despite widespread cultivation.
Case report focuses on a rare instance of severe allergic reaction to white grapes.

Observation:

A 28-year-old woman experienced two anaphylactic episodes after consuming white grapes.
Symptoms included urticaria, angioedema, pruritus, and dysphagia, requiring emergency treatment.

Findings:

Standard skin prick tests with commercial grape extract were negative.
Prick-by-prick testing with fresh grapes and juice, along with detected grape-specific IgE, confirmed allergy.
Commercial grape extracts may lack diagnostic sensitivity for grape allergy.

Implications:

Highlights the importance of prick-by-prick testing for diagnosing grape allergy when commercial extracts fail.
Suggests potential limitations in current commercial grape allergen extracts for diagnostic purposes.
Emphasizes the need for careful diagnostic approaches in suspected rare food allergies.