Related Experiment Video
Updated: Aug 18, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
Published on: April 14, 2016
Extemporaneous compounding of pain and symptom control medications
1Duke Production, Duke University Medical Center, Durham, NC 27707, USA. latta001@mc.duke.edu
Abstract:
This paper introduces a new series in the Journal on extemporaneously compounded dosage forms for symptom control. Some advantages and limitations of compounded medications are described and issues that clinicians should consider are mentioned. Topics that will be discussed in future papers in this series are described. Changes of compounding-related chapters of the United States Pharmacopeia from advisory statements to enforceable standards are discussed. As an example of important formulation considerations, some physical-chemical characteristics and route of administration characteristics of opioid analgesics are discussed.
Related Concept Videos
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Analgesia and Pain Management
Opioid Analgesics: Morphine and Other Natural Cogeners
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Agonism and Antagonism: Quantification
To quantify these effects, researchers use a dose-response curve, which provides valuable information about the potency and efficacy of a drug. Potency refers to...
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...

