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Updated: Aug 7, 2026

Isolation and Characterization of Mouse Antral Oocytes Based on Nucleolar Chromatin Organization
Published on: January 7, 2016
Oocyte-somatic cell communication
1Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA. david.albertini@tufts.edu
Abstract:
The physical interface between the female germ line and enveloping somatic cells is dynamically modified throughout the course of folliculogenesis. How selective pathways for communication between the oocyte and granulosa cell are established and regulated remains to be determined, but insights into the structural basis for this communication are emerging. This review summarizes the available evidence that supports the notion that the integration of oogenesis with folliculogenesis is achieved by regulated cell interactions between oocytes and granulosa cells.
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