Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gene expression in the developing embryo and fetus.

J Taylor1, H Fairburn, N Beaujean

  • 1Division of Gene Expression and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK.

Reproduction (Cambridge, England). Supplement
|November 26, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethics committees. Separate criteria should be drawn up for questionnaire based epidemiological studies.

BMJ (Clinical research ed.)·1996
Same author

Accident experience and notification rates in people with recent seizures, epilepsy or undiagnosed episodes of loss of consciousness.

QJM : monthly journal of the Association of Physicians·1995
Same author

The effects of fasting on the thermogenic, metabolic and cardiovascular responses to infused adrenaline.

The British journal of nutrition·1995
Same author

HIV risk: no impact on medical student specialty choice.

Rhode Island medicine·1995
Same author

Control of neuronal morphology in vitro: interplay between adhesive substrate forces and molecular instruction.

Journal of neuroscience research·1995
Same author

Structure of the hepatic control region of the human apolipoprotein E/C-I gene locus.

The Journal of biological chemistry·1995
Same journal

Reproduction in domestic ruminants V. Overview.

Reproduction (Cambridge, England). Supplement·2003
Same journal

Gene targeting in livestock.

Reproduction (Cambridge, England). Supplement·2003
Same journal

Reprogramming the genome: role of the cell cycle.

Reproduction (Cambridge, England). Supplement·2003
Same journal

The differential secretion of FSH and LH: regulation through genes, feedback and packaging.

Reproduction (Cambridge, England). Supplement·2003
Same journal

Growth and maturation of oocytes in vitro.

Reproduction (Cambridge, England). Supplement·2003
Same journal

Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans.

Reproduction (Cambridge, England). Supplement·2003
See all related articles

Gene expression patterns in embryos and fetuses reveal developmental insights. Rigorous interpretation of gene expression studies is crucial for accurate diagnostic markers and understanding developmental defects.

Area of Science:

  • Developmental biology
  • Genomics
  • Reproductive technologies

Background:

  • Gene expression patterns are critical for understanding normal embryonic and fetal development.
  • Altered gene expression is linked to abnormal phenotypes, offering insights into molecular mechanisms.
  • Gene expression changes may serve as predictive markers for developmental defects, especially in preimplantation embryo technologies.

Purpose of the Study:

  • To review the relevance of gene expression changes as diagnostic markers.
  • To discuss the interpretation and significance of gene expression studies in development.
  • To highlight the relationship between gene expression, protein, and epigenetic changes.

Main Methods:

  • Literature review of gene expression studies in embryonic and fetal development.

Related Experiment Videos

  • Analysis of the interpretation and functional significance of gene expression data.
  • Discussion of diagnostic marker potential in relation to protein and epigenetic factors.

    • Main Results:

    • Gene expression patterns provide information on normal development and molecular mechanisms of abnormalities.
    • Deviations in gene expression can potentially serve as predictive markers for developmental defects.
    • The functional significance of detected gene expression differences is often not defined.

    Conclusions:

    • Gene expression studies require rigorous design and interpretation for meaningful results.
    • Understanding stage- and tissue-specific gene expression is key to developmental biology.
    • The utility of gene expression as diagnostic markers depends on their correlation with protein and epigenetic changes.