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Related Experiment Videos

Left ventricular myxosarcoma in a dog.

R D Foale1, R A S White, R Harley

  • 1The Queen's Veterinary School Hospital, University of Cambridge, Madingley Road, Cambridge CB3 0ES.

The Journal of Small Animal Practice
|November 26, 2003
PubMed
Summary
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A Neopolitan mastiff with chronic diarrhea was found to have a pericardial myxosarcoma. Surgical removal led to recovery, but the tumor recurred, causing euthanasia.

Area of Science:

  • Veterinary Cardiology
  • Veterinary Oncology
  • Canine Pathology

Background:

  • Gastrointestinal signs like chronic diarrhea and weight loss can present diagnostic challenges in dogs.
  • Pericardial masses are rare in canine patients and can cause significant cardiac compromise.

Observation:

  • A two-year-old male Neopolitan mastiff presented with chronic diarrhea and weight loss unresponsive to initial diagnostics.
  • Echocardiography revealed a large, multilocular cyst-like pericardial mass compressing the heart.
  • Surgical excision of the mass from the left ventricular myocardium was performed.

Findings:

  • Histopathology confirmed the mass as a low-grade malignant myxosarcoma.
  • The dog initially recovered well, with no signs of recurrence for nine months post-surgery.

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  • Tumor recurrence with local metastasis was diagnosed 11 months post-surgery, leading to euthanasia.

    • Implications:

    • This case highlights the potential for cardiac myxosarcomas to present with extrathoracic signs such as chronic diarrhea.
    • Early diagnosis and surgical intervention can provide temporary remission, but the prognosis for canine pericardial myxosarcomas remains guarded due to recurrence risk.
    • Further research into the biological behavior and treatment strategies for canine cardiac tumors is warranted.