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Related Experiment Videos

Transbronchial needle aspiration: initial experience in routine diagnostic bronchoscopy.

Kay-Leong Khoo1, Gerald S W Chua, Amartya Mukhopadhyay

  • 1Division of Respiratory Medicine, Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Khookl@nuh.com.sg

Respiratory Medicine
|November 26, 2003
PubMed
Summary

Transbronchial needle aspiration (TBNA) is a safe and effective tool for diagnosing mediastinal diseases, even for inexperienced teams when using rapid on-site evaluation (ROSE). This procedure offers a high diagnostic yield for both benign and malignant conditions.

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Area of Science:

  • Pulmonology
  • Oncology
  • Cytopathology

Background:

  • Transbronchial needle aspiration (TBNA) is underutilized despite its diagnostic potential for lung cancer and other conditions.
  • Concerns regarding yield, safety, and expertise limit widespread adoption of TBNA.
  • Rapid on-site evaluation (ROSE) can potentially improve TBNA's effectiveness.

Purpose of the Study:

  • To assess the clinical utility and diagnostic yield of TBNA.
  • To evaluate TBNA as an adjunct to diagnostic bronchoscopy in an inexperienced setting.
  • To include both malignant and benign indications for TBNA.

Main Methods:

  • A University Teaching Hospital, new to the procedure, was the setting.
  • Forty-five consecutive patients underwent TBNA during diagnostic bronchoscopy over two years.

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  • ROSE was available throughout the study period.

    • Main Results:

    • TBNA achieved a 65% yield for evaluating mediastinal diseases (benign and malignant).
    • The overall diagnostic utility across all indications was 71%.
    • No complications were reported during the study.

    Conclusions:

    • TBNA is a safe and valuable adjunct to diagnostic bronchoscopy in clinical practice.
    • Satisfactory diagnostic yield is achievable with TBNA, even for inexperienced teams, when ROSE is utilized.
    • TBNA enhances diagnostic capabilities for a range of mediastinal pathologies.