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Fulminant citrobacter meningitis with multiple periventricular abscesses in a three-month-old infant
P Anoop1, M A Anjay, Johny Vincent
1Institute of Maternal and Child Health, Medical College, Calicut, Kerala, India. dranoopp@rediffmail.com
Abstract:
Citrobacter, a Gram-negative enteric bacillus, is a rare cause of septicemia and meningitis, seldom reported beyond the neonatal period. It is characterized by a fulminant clinical course and a high incidence of complications, including brain abscesses. We studied a three-month-old infant with Citrobacter meningitis, who developed acute communicating hydrocephalus and multiple periventricular brain abscesses while on treatment. The patient died, despite intensive antibiotic treatment directed towards the causative organism, C. diversus.
Insights
Citrobacter diversus meningitis is rare in infants beyond the neonatal period. This case highlights severe complications like hydrocephalus and brain abscesses, even with treatment, leading to a fatal outcome.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Pediatric Neurology
Background:
- Citrobacter species are Gram-negative enteric bacilli.
- Citrobacter infections, particularly septicemia and meningitis, are uncommon outside the neonatal period.
- These infections often present with severe clinical courses and complications.
Observation:
- A three-month-old infant developed Citrobacter meningitis.
- The infant experienced acute communicating hydrocephalus.
- Multiple periventricular brain abscesses formed during antibiotic treatment.
Findings:
- Citrobacter diversus caused meningitis in an infant.
- Despite intensive antibiotic therapy, the infant's condition progressed.
- The patient developed severe neurological complications including hydrocephalus and brain abscesses.
Implications:
- This case underscores the potential severity of Citrobacter meningitis in infants.
- It highlights the challenges in treating invasive Citrobacter infections.
- Early recognition and aggressive management are crucial for potential better outcomes in rare pediatric meningitis cases.
Related Concept Videos
Bacterial Meningitis
Viral Meningitis
Cryptococcal Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Brain Abscess l: Introduction

