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Updated: Aug 30, 2026
Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary
Frank J H Gijsen1, Remko M Oortman, Jolanda J Wentzel
1Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands. f.gijsen@erasmusmc.nl
Abstract:
The true 3-dimensional neointimal thickness distribution in sirolimus-eluting stents was investigated in relation to the shear stress distribution, which was obtained from computational fluid dynamics calculations. Small pits were observed between the stent struts in all patients, and a significant inverse relation between neointimal thickness and shear stress was found, indicating that deeper pits were present in the outside curve of the stented segments.
