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Updated: Aug 30, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Multifaceted functions of B cells in chronic hepatitis C virus infection
1Research Laboratories, Department of Infectious Diseases, IRCCS Policlinico San Matteo and University of Pavia, Via Taramelli, 5, 27100 Pavia, Italy. m.mondelli@smatteo.pv.it
Abstract:
Hepatitis C virus (HCV) elicits T- and B-cell responses which are believed to play an important role in infection control. B cells have generally been neglected because they do not seem to significantly influence the course of HCV infection. In this review, B lymphocytes are viewed both as classical antibody producing cells, with the hypervariable region 1 being a biologically relevant target protein and as a model of virus-host interaction in lymphoproliferative disorders characteristic of persistent microbial infections.
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