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Prediction of hormone responsiveness by mammographic parenchymal pattern in advanced primary breast cancer
N S Nielsen1, J Andersen, H S Poulsen
1Dept. of Radiology R., Aarhus University Hospital, Denmark.
Breast Cancer Research and Treatment
|January 1, 1992
Abstract:
Ninety-two women with advanced, unilateral breast cancer were classified according to the Wolfe and Nottingham classifications of mammographic parenchymal pattern (MPP). Both classifications of MPP were significantly correlated to the estrogen receptor (ER) status of the breast carcinoma, but could not be used for prediction of response to hormonal therapy. Age distribution was significantly different among Wolfe types as well as between ER groups, but a multiple regression analysis showed that both age and Wolfe pattern were significant and independent predictors of the ER status.