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Related Experiment Videos

Atypical cerebral laterality in adults with persistent developmental stuttering.

A L Foundas1, D M Corey, V Angeles

  • 1Department of Psychiatry and Neurology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA. foundas@tulane.edu

Neurology
|November 26, 2003
PubMed
Summary

Adults who stutter show atypical brain asymmetries in prefrontal and occipital lobes, unlike fluent individuals. Language deficits in stuttering are linked to reduced prefrontal and occipital lobe volumes.

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Area of Science:

  • Neuroscience
  • Human Anatomy
  • Speech and Language Pathology

Background:

  • Consistent brain asymmetries include a larger right prefrontal and left occipital lobe.
  • Atypical cerebral laterality is linked to increased neural risk for developmental stuttering.

Purpose of the Study:

  • Investigate if atypical prefrontal and occipital lobe asymmetries are more prevalent in adults who stutter compared to fluent controls.
  • Determine associations between lobar size/asymmetry patterns and stuttering severity or language abilities.

Main Methods:

  • Volumetric MRI scans were used to measure prefrontal and occipital lobe volumes in adults with persistent developmental stuttering (n=16) and matched controls (n=16).
  • Brain volumes were calculated proportionally to hemisphere volume.

Related Experiment Videos

  • Language and stuttering assessments were conducted.

    • Main Results:

    • No significant differences in hemisphere or total brain volumes were observed between groups.
    • Control subjects exhibited typical asymmetries (larger right prefrontal, larger left occipital lobes).
    • Adults who stutter showed atypical asymmetries; language deficits correlated with reduced prefrontal and occipital volumes.

    Conclusions:

    • Developmental stuttering is associated with atypical prefrontal and occipital lobe asymmetries.
    • Language processing deficits in adults who stutter are linked to specific anatomical measures, including prefrontal and occipital volume reduction.