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Subthalamic lesion and paroxysmal tonic spasms.
Pedro J Garcia-Ruiz1, Vicente Villanueva, Eva Gutierrez-Delicado
1Department of Neurology, Fundación Jimenez Díaz, Madrid, Spain. pgarcia@fjd.es
Movement Disorders : Official Journal of the Movement Disorder Society
|November 26, 2003
Summary
A rare subthalamic lesion caused paroxysmal tonic spasms. Video-electroencephalographic recording confirmed the nonepileptic episodes, which responded well to carbamazepine treatment.
Area of Science:
- Neuroscience
- Neurology
- Movement Disorders
Background:
- Paroxysmal dyskinesias are rare movement disorders.
- Subthalamic lesions causing these symptoms are exceptionally uncommon.
Observation:
- A patient presented with paroxysmal tonic spasms.
- A well-defined lesion in the subthalamic area was identified.
- Video-electroencephalographic recording confirmed the nonepileptic nature of the episodes.
Findings:
- Detailed clinical features of the subthalamic lesion-induced paroxysmal dyskinesia were documented.
- The patient exhibited an excellent response to carbamazepine therapy.
Implications:
- This case highlights carbamazepine as a potential treatment for subthalamic paroxysmal dyskinesias.
- Understanding the neurobiology of subthalamic lesions is crucial for diagnosing and managing rare movement disorders.