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[Leiomyosarcoma of the breast]
Miroslav Lesar1, Stjepan Juzbasić, Mladen Stanec
1Klinika za tumore, Zagreb, Hrvatska. miroslav.lesar@zg.hinet.hr
Summary
A rare breast cancer, leiomyosarcoma mammae, was diagnosed in a 62-year-old patient. Treatment involved radical surgery and radiotherapy due to the tumor's characteristics.
Area of Science:
- Oncology
- Pathology
Background:
- Leiomyosarcoma mammae is an exceptionally rare primary malignant breast tumor.
- Diagnosis can be challenging, requiring comprehensive pathological analysis.
Observation:
- A 62-year-old patient presented with a palpable breast change.
- Preoperative imaging and cytology were inconclusive regarding malignancy.
- Biopsy, pathohistology, and immunoanalysis confirmed leiomyosarcoma mammae.
Findings:
- The patient underwent radical breast excision and axillary lymph node dissection.
- Due to cardiologic complications during surgery, locoregional radiotherapy was added.
- This case represents one of only 14 reported instances of breast leiomyosarcoma.
Implications:
- Management strategies for this rare tumor adapt principles used for other breast cancers and leiomyosarcomas.
- Highlights the importance of thorough pathological examination for rare breast malignancies.
- Contributes to the limited literature on breast leiomyosarcoma, informing future treatment approaches.