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A probabilistic model for the extraction of expression levels from oligonucleotide arrays
1Department of Computer Science, University of Sheffield, 211 Portobello Street, Regent Court, Sheffield S4 1DP, U.K. m.milo@sheffield.ac.uk
Biochemical Society Transactions
|December 4, 2003
Abstract:
In this work we present a probabilistic model to estimate summaries of Affymetrix GeneChip probe level data. Comparisons with two different models were made both on a publicly available dataset and on a study performed in our laboratory, showing that our model performs better for consistency of fold change.