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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

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Updated: Jun 29, 2026

Cell Population Analyses During Skin Carcinogenesis
06:53

Cell Population Analyses During Skin Carcinogenesis

Published on: August 21, 2013

Axillary basal cell carcinoma.

Benjamin W LeSueur1, David J DiCaudo, Suzanne M Connolly

  • 1Department of Dermatology, Mayo Clinic Scottsdale, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA. lesueur.benjamin@mayo.edu

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|December 4, 2003
PubMed
Summary
This summary is machine-generated.

Basal cell carcinoma (BCC) is a rare skin cancer that can occur in the axilla. This study reviewed 14 patients, finding that factors beyond sun exposure may contribute to its development.

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Basal cell carcinoma (BCC) is infrequently found in the axilla, with only 18 prior global case reports.
  • This study details an 11-year institutional experience with axillary BCC.

Purpose of the Study:

  • To document the clinical and pathological features of axillary basal cell carcinoma.
  • To investigate potential risk factors and outcomes for this rare skin cancer presentation.

Main Methods:

  • Retrospective review of patient medical records.
  • Analysis of biopsy specimens for histological classification.

Main Results:

  • Fourteen patients with 15 axillary BCCs were identified.
  • The average age was 65.6 years, with an average lesion size of 10.8 mm.
  • Nine patients had a history of skin cancer on sun-exposed areas; one had basal cell nevus syndrome. Other risk factors included ionizing radiation and sunburn in separate cases. No immunosuppression or other malignancies were noted. Histologic subtypes were less aggressive, with one recurrence.

Conclusions:

  • Axillary BCC is a rare entity.
  • Non-ultraviolet radiation factors may play a role in axillary BCC development, particularly in sun-protected zones.
  • Complete skin examinations, including sun-protected areas, are crucial, especially for patients with a prior skin cancer history.