Successful management of a pregnant woman with heterozygous protein C deficiency using activated protein C

Related Experiment Video

Updated: Aug 30, 2026

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
09:04

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods

Published on: September 10, 2018

Kentaroh Sekiyama1, Hiroaki Itoh, Norimasa Sagawa

  • 1Department of Gynecology and Obstetrics, Clinical Sciences for Pathological Organs, Kyoto University Graduate School of Medicine, Kyoto, Japan.

The Journal of Obstetrics and Gynaecology Research
|December 4, 2003
PubMed

Heterozygous protein C deficiency frequently causes deep vein thrombosis during pregnancy. We report the successful management of delivery using activated protein C concentrate in a patient with heterozygous protein C deficiency, who developed deep vein thrombosis in mid gestation.

Related Concept Videos

Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...