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Related Experiment Videos

A young man with a renal colic.

F Barbey1, C Matthieu, G Nseir

  • 1Department of Nephrology, University Hospital, Lausanne, Switzerland. frederic.barbey@chuv.hospvd.ch

Journal of Internal Medicine
|December 4, 2003
PubMed
Summary
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A young man experienced severe hypertension due to renal infarction caused by fibromuscular dysplasia (FMD). This rare case highlights FMD

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Vascular Biology

Background:

  • Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease primarily affecting young women.
  • Renal artery stenosis due to FMD can lead to renovascular hypertension.
  • Renal infarction is uncommon in young individuals without cardiovascular risk factors.

Observation:

  • A 35-year-old man presented with flank pain and hematuria, initially diagnosed as ureteral colic.
  • He later developed a severe hypertensive crisis.
  • Investigations revealed massive renal infarction attributed to medial fibromuscular dysplasia (FMD).

Findings:

  • The patient had no prior cardiovascular issues or significant atheromatous disease.
  • FMD was the underlying cause of renal artery occlusion and subsequent infarction.

Related Experiment Videos

  • A delayed hypertensive response was noted after the renovascular insult.

    • Implications:

    • This case challenges typical presentations of FMD and renal infarction.
    • It underscores the importance of considering FMD in young adults with unexplained renovascular events.
    • Further research into the pathophysiology of delayed hypertension in renovascular disease is warranted.