Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tomatoes have natural anti-thrombotic effects.

J Yamamoto1, T Taka, K Yamada

  • 1Laboratory of Physiology, Faculty of Nutrition and High Technology Research Centre, Kobe Gakuin University, Kobe, Japan. yamamoto@nutr.kobegakuin.ac.jp

The British Journal of Nutrition
|December 4, 2003
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical starting time in the morning versus the afternoon: propensity score matched analysis of operative outcomes following laparoscopic colectomy for colorectal cancer.

Surgical endoscopy·2018
Same author

Relationship between copper and lipids and atherogenic indices soon after birth in Japanese preterm infants of 32-35 weeks.

Journal of developmental origins of health and disease·2016
Same author

Effects of probiotic Lactobacillus brevis KB290 on incidence of influenza infection among schoolchildren: an open-label pilot study.

Letters in applied microbiology·2014
Same author

Effects of breastfeeding on the risk factors for metabolic syndrome in preterm infants.

Journal of developmental origins of health and disease·2014
Same author

Oral administration of Lactobacillus brevis KB290 to mice alleviates clinical symptoms following influenza virus infection.

Letters in applied microbiology·2013
Same author

Effects of the autonomic nervous system on functional neuroimaging: analyses based on the vector autoregressive model.

Advances in experimental medicine and biology·2012

Tomato extracts show significant anti-thrombotic effects, with one variety inhibiting thrombus formation and promoting clot breakdown. This research highlights tomatoes as a potential dietary approach for preventing arterial thrombotic diseases.

Area of Science:

  • Cardiovascular Research
  • Nutritional Science
  • Pharmacology

Background:

  • Arterial thrombotic diseases are a major health concern in developed nations.
  • Dietary factors, including an inappropriate diet, are significant risk factors for thrombotic events.
  • An anti-thrombotic diet presents a potential strategy for disease prevention.

Purpose of the Study:

  • To evaluate the anti-thrombotic effects of tomato extracts.
  • To identify specific tomato varieties possessing anti-thrombotic properties.
  • To assess the efficacy of tomato extracts in preventing arterial thrombosis.

Main Methods:

  • In vitro assessment of anti-thrombotic potential using a shear-induced platelet-function test (haemostatometry).
  • In vivo evaluation of promising tomato extracts in a laser-induced thrombosis model in mice.

Related Experiment Videos

  • Analysis of thrombus formation inhibition and thrombolytic effects.

    • Main Results:

    • One tomato variety (KG99-4) demonstrated significant anti-thrombotic activity in both in vitro and in vivo models.
    • KG99-4 extract effectively inhibited the formation of platelet-rich thrombi.
    • The KG99-4 extract also exhibited a notable thrombolytic effect, aiding in clot dissolution.

    Conclusions:

    • Haemostatometry is a reliable method for detecting and characterizing the anti-thrombotic potential of fruits and vegetables.
    • Tomato variety KG99-4 possesses significant anti-thrombotic and thrombolytic properties.
    • Dietary intake of specific tomato varieties may offer a practical approach to preventing arterial thrombotic diseases.