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Updated: Aug 14, 2026

Generation of Genetically Modified Mice through the Microinjection of Oocytes
Published on: June 15, 2017
Transgenic animals in biomedicine and agriculture: outlook for the future
M B Wheeler1, E M Walters, S G Clark
1366 Animal Sciences Laboratory, Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1207 W. Gregory Dr., Urbana, IL 61801, USA. mbwheele@uiuc.edu
Abstract:
Transgenic animals are produced by introduction of 'foreign' deoxyribonucleic acid (DNA) into preimplantation embryos. The foreign DNA is inserted into the genetic material and may be expressed in tissues of the resulting individual. This technique is of great importance to many aspects of biomedical science including gene regulation, the immune system, cancer research, developmental biology, biomedicine, manufacturing and agriculture. The production of transgenic animals is one of a number of new and developing technologies that will have a profound impact on the genetic improvement of livestock. The rate at which these technologies are incorporated into production schemes will determine the speed at which we will be able to achieve our goal of more efficiently producing livestock, which meets consumer and market demand.
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