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Updated: Aug 30, 2026

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Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
Published on: June 20, 2014
Design and pharmacology of peptoids and peptide-peptoid hybrids based on the melanocortin agonists core tetrapeptide
Jerry Ryan Holder1, Rayna M Bauzo, Zhimin Xiang
1Department of Medicinal Chemistry, University of Florida, PO Box 100485, Gainesville, FL 32610, USA.
Bioorganic & Medicinal Chemistry Letters
|December 4, 2003
Abstract:
A series of N-substituted glycine oligomers (peptoids) and peptide-peptoid hybrids were synthesized based on the Ac-His-Phe-Arg-Trp-NH(2) tetrapeptide template. The compounds were pharmacologically characterized at the mouse melanocortin receptors (MC1R, MC3R-MC5R) for agonist activity.
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