Risk factors for overall and persistent diarrhoea in infancy in Antalya, Turkey: a cohort study

N Etiler1, S Velipasaoglu, M Aktekin

  • 1Department of Public Health, Kocaeli University Medical Faculty, Halk Sagligi Anabilim Dali, Derince, Kocaeli 41900, Turkey. etlier@kou.edu.tr

Public Health
|December 4, 2003
PubMed

Insights

Maternal education and socioeconomic factors significantly impact infant diarrhea incidence. Poor living conditions and infant health issues also increase risks for overall and persistent diarrhea in infants.

Area of Science:

  • Pediatrics
  • Public Health
  • Epidemiology

Background:

  • Diarrhoea remains a leading cause of infant morbidity and mortality globally.
  • Identifying risk factors is crucial for developing effective prevention strategies.
  • Socioeconomic and environmental determinants play a significant role in infant health outcomes.

Purpose of the Study:

  • To investigate factors influencing the incidence of overall and persistent diarrhoea in infants.
  • To assess the association between maternal education, socioeconomic status, environmental factors, infant characteristics, and nutritional status with diarrhoea incidence.
  • To provide evidence for targeted public health interventions.

Main Methods:

  • Prospective cohort study involving 204 infants followed for one year in Antalya, Turkey.
  • Morbidity surveillance and anthropometric measurements conducted via bi-monthly home visits.
  • Statistical analyses including relative risks, confidence intervals, and logistic regression.

Main Results:

  • Maternal education level was strongly associated with both overall and persistent diarrhoea risk.
  • Living in a slum, crowded housing, lack of a kitchen, and unhygienic toilets increased diarrhoea incidence.
  • Infant factors like preterm birth, low birth weight, delayed first breastfeeding, and malnutrition (underweight, stunting, wasting) were significant risk factors.

Conclusions:

  • Maternal education is a key protective factor against infant diarrhoea.
  • Improving socioeconomic conditions and environmental hygiene can reduce diarrhoea burden.
  • Early identification and management of infant health and nutritional issues are vital for preventing diarrhoea.

Related Concept Videos

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
Anatomy of the Intestines01:53

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.Small IntestinesThe small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small intestine...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...