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Risk factors for overall and persistent diarrhoea in infancy in Antalya, Turkey: a cohort study
N Etiler1, S Velipasaoglu, M Aktekin
1Department of Public Health, Kocaeli University Medical Faculty, Halk Sagligi Anabilim Dali, Derince, Kocaeli 41900, Turkey. etlier@kou.edu.tr
Insights
Maternal education and socioeconomic factors significantly impact infant diarrhea incidence. Poor living conditions and infant health issues also increase risks for overall and persistent diarrhea in infants.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Diarrhoea remains a leading cause of infant morbidity and mortality globally.
- Identifying risk factors is crucial for developing effective prevention strategies.
- Socioeconomic and environmental determinants play a significant role in infant health outcomes.
Purpose of the Study:
- To investigate factors influencing the incidence of overall and persistent diarrhoea in infants.
- To assess the association between maternal education, socioeconomic status, environmental factors, infant characteristics, and nutritional status with diarrhoea incidence.
- To provide evidence for targeted public health interventions.
Main Methods:
- Prospective cohort study involving 204 infants followed for one year in Antalya, Turkey.
- Morbidity surveillance and anthropometric measurements conducted via bi-monthly home visits.
- Statistical analyses including relative risks, confidence intervals, and logistic regression.
Main Results:
- Maternal education level was strongly associated with both overall and persistent diarrhoea risk.
- Living in a slum, crowded housing, lack of a kitchen, and unhygienic toilets increased diarrhoea incidence.
- Infant factors like preterm birth, low birth weight, delayed first breastfeeding, and malnutrition (underweight, stunting, wasting) were significant risk factors.
Conclusions:
- Maternal education is a key protective factor against infant diarrhoea.
- Improving socioeconomic conditions and environmental hygiene can reduce diarrhoea burden.
- Early identification and management of infant health and nutritional issues are vital for preventing diarrhoea.
Abstract:
The aim of this study was to identify factors that influence the incidence of diarrhoea in infancy. The study was a prospective cohort study conducted in two primary healthcare unit areas in Antalya, Turkey. A total of 204 infants were followed until they were aged 1 year. Morbidity surveillance and anthropometric measurements were carried out by home visits every 2 months. The average incidences were found to be 2.76 episodes per child-year for overall diarrhoea and 18.56 episodes per 100 child-years for persistent diarrhoea. Relative risks, confidence intervals and logistic regression analyses were used to assess the associations. For both overall diarrhoea and persistent episodes, increased risks were associated with having an uneducated mother (RR=1.89 and 5.33, respectively) and a self-employed father (RR=1.89 and 3.77, respectively). Among environmental factors, living in a slum was associated with both overall (RR=1.68) and persistent (RR=2.69) diarrhoea, whereas living in a crowded house (RR=1.70), having no kitchen (RR=2.27) or having an unhygienic toilet (RR=1.93) were found to be significant for overall episodes alone. Factors related to the infant were preterm birth (RR=1.64), low birth weight (RR=2.05), and first breastfeed given more than 1 h after birth (RR=1.64). Nutritional status was also associated with overall or persistent diarrhoea: underweight children (RR=2.15, persistent diarrhoea only), stunted children (RR=1.67 and 2.14, respectively) or wasted children (RR=1.54 and 3.20, respectively). By logistic regression analysis, both overall and persistent diarrhoea were found to be associated with mother's education.
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