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Long-term genetic effects of radiation exposure
1Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK. yed2@le.ac.uk
Mutation Research
|December 4, 2003
Abstract:
To date, there has been little experimental knowledge on the genetic risks of human exposure to ionising radiation for humans. Recent data suggest that hypervariable tandem repeat minisatellite loci provide a useful and sensitive experimental approach for monitoring radiation-induced germline mutation in humans. Here, I review the results of studies on minisatellite mutation rates in human populations exposed to radioactive fallout after the Chernobyl accident and nuclear weapon tests in Kazakhstan.