Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Bronchiolar disorders.

Jay H Ryu¹, Jeffrey L Myers, Stephen J Swensen

¹Division of Pulmonary and Critical Care Medicine, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA. ryu.jay@mayo.edu

American Journal of Respiratory and Critical Care Medicine

|December 4, 2003

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Use of Bronchoscopic Cryobiopsy in Evaluating Interstitial Lung Disease: Radiologic Predictors of Diagnostic Yield and Safety.

Mayo Clinic proceedings·2026

Same author

In Reply.

Archives of pathology & laboratory medicine·2026

Same author

Pulmonary venoocclusive disease/pulmonary capillary hemangiomatosis: Inadequacy of clinico-radiologic features in diagnosis.

Human pathology·2026

Same author

Lung Auscultation for Detecting Interstitial Lung Disease in Patients with Newly Diagnosed Systemic Sclerosis: Retrospective Cohort Study.

Diagnostics (Basel, Switzerland)·2026

Same author

Spontaneous pneumothorax-associated with genetic disorders.

Therapeutic advances in respiratory disease·2026

Same author

Pulmonary Hypertension Associated With Interstitial Lung Disease: State-of-the-Art Review.

The European respiratory journal·2026

Same journal

When an Exacerbation Signals a Different Future in non-severe asthma.

American journal of respiratory and critical care medicine·2026

Same journal

Aim High-Stay Stable: Rethinking Treatment Success in COPD.

American journal of respiratory and critical care medicine·2026

Same journal

Three versus six weeks of corticosteroids for mild immune-related pneumonitis: a randomized trial.

American journal of respiratory and critical care medicine·2026

Same journal

Signal in the Noise: Polygenic Scores and the Problem of Defining Idiopathic Pulmonary Fibrosis.

American journal of respiratory and critical care medicine·2026

Same journal

Do mtDNA fragmentomic peaks reflect cancer biology or preanalytical and technical artifacts in NSCLC?

American journal of respiratory and critical care medicine·2026

Same journal

Short for Their Age: Interpreting Whole-Genome Telomere Length in Idiopathic Pulmonary Fibrosis.

American journal of respiratory and critical care medicine·2026

See all related articles

This study proposes a classification scheme for bronchiolar disorders, distinguishing primary conditions from those secondary to parenchymal or large airway diseases. This approach aims to clarify nomenclature and improve clinical understanding of lung diseases.

Area of Science:

Pulmonary Medicine
Pathology
Respiratory System

Background:

Bronchiolar abnormalities are common but present with confusing nomenclature due to overlapping histopathologic patterns.
Existing classifications lack clarity regarding etiology and pathogenesis of bronchiolar diseases.

Purpose of the Study:

To present a systematic classification scheme for bronchiolar disorders.
To differentiate primary bronchiolar diseases from those associated with parenchymal or large airway conditions.
To aid in understanding the clinical relevance of bronchiolar lesions.

Main Methods:

Review and synthesis of existing literature on bronchiolar histopathology.
Development of a hierarchical classification system based on disease predominance.

Related Experiment Videos

Categorization of disorders into primary bronchiolar, parenchymal with bronchiolar involvement, and large airway diseases with bronchiolar involvement.

Main Results:

Proposed classification separates disorders into three main groups: primary bronchiolar disorders, parenchymal disorders with prominent bronchiolar involvement, and large airway diseases with bronchiolar involvement.
Identified specific examples within each category, including constrictive bronchiolitis, hypersensitivity pneumonitis, and chronic obstructive pulmonary disease.
Highlighted that some patterns are specific to clinical contexts, while others are nonspecific.

Conclusions:

A clear classification scheme is essential for understanding bronchiolar diseases.
Correlating histopathologic patterns with clinical, physiological, and radiological findings is crucial for determining clinical relevance.
This framework aims to reduce nomenclature confusion and enhance diagnostic accuracy.