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Related Experiment Videos

Prescribing patterns for patients with posttraumatic stress disorder.

Thomas A Mellman1, Robin E Clark, William J Peacock

  • 1Department of Psychiatry, Dartmouth Hitchcock Medical Center, On Medical Center Drive, Lebanon, New Hampshire 03756, USA. mellman@dartmouth.edu

Psychiatric Services (Washington, D.C.)
|December 4, 2003
PubMed
Summary

Prescribing patterns for posttraumatic stress disorder (PTSD) in nonveterans reveal aggressive medication use, especially when co-occurring with major depression. Findings highlight discrepancies with treatment guidelines.

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Area of Science:

  • Psychiatry
  • Pharmacology
  • Public Health

Background:

  • Limited data exists on medication prescribing for posttraumatic stress disorder (PTSD), primarily from male veteran populations.
  • Understanding prescribing patterns in diverse, community-based samples is crucial for effective treatment.
  • This study addresses the gap by examining nonveteran populations with high female representation.

Purpose of the Study:

  • To comprehensively evaluate medication prescribing patterns for individuals diagnosed with posttraumatic stress disorder (PTSD).
  • To compare prescribing patterns between patients with PTSD, major depression alone, and comorbid PTSD and major depression.
  • To assess prescribing trends in a community-based, nonveteran sample.

Main Methods:

  • Analysis of prescription claims data for New Hampshire Medicaid recipients in December 1999.

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  • Inclusion criteria: diagnostic codes for PTSD, major depression alone, or comorbid PTSD and major depression.
  • Comparison of medication prescription frequencies across the three patient groups.

    • Main Results:

    • Patients with PTSD were predominantly women receiving community mental health services.
    • Selective serotonin reuptake inhibitors were more common for major depression than PTSD.
    • Atypical antipsychotics and other novel antidepressants were more frequently prescribed for PTSD, especially when comorbid with major depression.

    Conclusions:

    • Outpatients with PTSD, particularly those with comorbid major depression, receive aggressive pharmacotherapy.
    • Observed prescribing patterns show discrepancies with established treatment guidelines.
    • Trends in nonveteran populations mirror those found in veteran samples.