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Azygos arch valves: prevalence and appearance at contrast-enhanced CT
Benjamin M Yeh1, Fergus V Coakley, Henry C Sanchez
1Departments of Radiology and Pathology, University of California San Francisco, 505 Parnassus Ave, Box 0628, M 372, San Francisco, CA 94143-0628, USA. benyeh@itsa.ucsf.edu
Insights
Azygos arch valves are common, appearing in over 68% of contrast-enhanced CT scans. High injection rates and right arm contrast injections increase the likelihood of visualizing these azygos valves.
Area of Science:
- Radiology
- Anatomy
- Medical Imaging
Background:
- The azygos arch is a venous structure in the thorax.
- Azygos valves are leaflets within the azygos arch, similar to venous valves elsewhere.
- Their prevalence and appearance on imaging are not well-established.
Purpose of the Study:
- To determine the frequency of azygos arch valves.
- To describe the imaging appearance of azygos valves using computed tomography (CT).
- To investigate factors influencing the visualization of azygos valves during contrast-enhanced CT.
Main Methods:
- Retrospective review of 309 contrast-enhanced spiral CT chest examinations.
- Assessment for contrast material reflux into the azygos arch and focal bulges.
- Definition of an azygos valve based on contrast material contour within the arch.
- Statistical comparison of reflux rates based on injection rate and arm used.
Main Results:
- Azygos valves were visualized in 105 (68.2%) of 309 examinations.
- Contrast reflux into the azygos arch occurred in 49.8% of scans.
- Valves were more frequently seen with high injection rates (64.8%) and right arm injections (76% in high-rate group).
- Refluxed contrast appeared as discrete collections within valve cusps in 44.8% of positive reflux cases.
Conclusions:
- Azygos arch valves are a common finding on contrast-enhanced CT.
- Higher contrast injection rates and right arm injections enhance the detection of azygos valves.
- These findings have implications for interpreting thoracic venous anatomy on CT.
Purpose:
To evaluate the prevalence and appearance of azygos arch valves at intravenous contrast material-enhanced computed tomography (CT).
Materials And Methods:
Findings of 309 intravenous contrast-enhanced spiral CT examinations of the chest were retrospectively reviewed. The presence of contrast material reflux into the azygos arch and of a focal bulge in the azygos arch was recorded. An azygos valve was considered present if contrast material with a curvilinear posterior contour was seen in the azygos arch. The chi2 test was used to compare the frequency of contrast material reflux into the azygos vein for high and low rates of contrast material injection and for right and left arm injection.
Results:
Reflux of contrast material into the azygos arch occurred at 154 (49.8%) of 309 examinations, and valves were seen on images of 105 (68.2%) examinations. A focal bulge was seen in the azygos arch on images of 86 (81.9%) of 105 examinations with an azygos valve. Contrast material refluxed more frequently into the azygos vein in examinations with high rates of injection (83 of 128 examinations, 64.8%) than in those with low rates of injection (71 of 181, 39.2%, P <.001). Among the patients with high rates of injection, contrast material refluxed more frequently into the azygos vein with the right arm injection than with left arm injection (53 of 70, 76% vs 30 of 58, 52%, P <.01). Refluxed contrast material appeared as discrete collections within cusps of the azygos valves on images of 69 (44.8%) of 154 examinations.
Conclusion:
Valves in the azygos arch are common and more frequently seen at CT when high injection rates and right arm injections are used.
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