Related Experiment Video

Updated: Jul 27, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Safety of endobronchial biopsy in 170 children with chronic respiratory symptoms

P S Salva1, C Theroux, D Schwartz

  • 1Pediatric Pulmonology of Western New England, Springfield, Massachusetts, USA. pedipulm@cox.net

Thorax
|December 4, 2003
PubMed

Insights

Pediatric bronchial biopsy is safe and effective for diagnosing chronic respiratory symptoms in children. This outpatient procedure provides adequate specimens for evaluation with minimal complications, encouraging its clinical use.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Medical Procedures

Background:

  • Limited data exists on pediatric bronchial biopsy safety and efficacy.
  • Concerns regarding procedure safety have restricted its use in children.
  • This study aimed to develop a safe and effective method for pediatric bronchial biopsy.

Purpose of the Study:

  • To evaluate the safety and efficacy of endobronchial biopsy in children.
  • To establish a reliable method for obtaining adequate biopsy specimens in pediatric patients.
  • To encourage the use of bronchial biopsy in diagnosing pediatric respiratory conditions.

Main Methods:

  • 170 children (2.5-16 years) with chronic respiratory symptoms underwent the procedure.
  • General anesthesia and a laryngeal mask airway were used.
  • Bronchoalveolar lavage and at least three endobronchial biopsies were obtained via flexible bronchoscope.

Main Results:

  • The procedure was safe, with no significant complications like pneumothorax or excessive bleeding.
  • Average procedure and recovery times were 12 and 90 minutes, respectively.
  • The primary limitation was airway size relative to the bronchoscope.

Conclusions:

  • Endobronchial biopsy is a safe and effective procedure for evaluating pediatric chronic respiratory symptoms.
  • The method yields adequate specimens for diagnosis.
  • Clinicians should consider incorporating this procedure into their diagnostic toolkit for children.
Abstract

More Related Videos

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies04:10

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies

Published on: July 19, 2024

Related Concept Videos

Assessment of Respiration01:23

Assessment of Respiration

The respiratory system's basic structures and primary functions lay the foundation for nurses' comprehensive respiratory assessments. This assessment includes subjective and objective data to gauge the patient's respiratory health.
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like asthma or COPD,...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...