Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent developments in micro-diffraction on protein crystals.

Christian Riekel1

  • 1European Synchrotron Radiation Facility, BP 220, F-38043 Grenoble, France.

Journal of Synchrotron Radiation
|December 4, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synchrotron Radiation-Assisted Oxidation of Gold Nanoparticles.

ACS nanoscience Au·2026
Same author

Recent Advances in Amyloids Structural Studies and Thin Film Applications.

Molecules (Basel, Switzerland)·2025
Same author

Exploring the Unique Properties and Superior Schwann Cell Guiding Abilities of Spider Egg Sac Silk.

ACS applied bio materials·2025
Same author

Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers.

Nature communications·2024
Same author

Insights into the material properties of dragline spider silk affecting Schwann cell migration.

International journal of biological macromolecules·2023
Same author

Mesoscale Confinement in Bagworm Silk: A Hidden Structural Organization.

Nano letters·2023
Same journal

Launching a new era for Short Communications in Journal of Synchrotron Radiation.

Journal of synchrotron radiation·2026
Same journal

Sagittal collimating diaboloid: a new grazing-incidence mirror surface for higher-throughput resonant inelastic X-ray scattering spectrometers.

Journal of synchrotron radiation·2026
Same journal

Synchrotron X-ray tomography and spectroscopy in numismatics: disclosing counterfeit practices in medieval silver coins.

Journal of synchrotron radiation·2026
Same journal

The Big Data Science Center at the Shanghai Synchrotron Radiation Facility: the architecture of the superfacility.

Journal of synchrotron radiation·2026
Same journal

A robotic and high-throughput X-ray micro-computed tomography workflow.

Journal of synchrotron radiation·2026
Same journal

Evolution of hierarchical phase-contrast tomography on the European Synchrotron beamlines BM05 and BM18: a whole adult human brain imaging case study.

Journal of synchrotron radiation·2026
See all related articles

Protein crystallography micro-diffraction and micro small-angle X-ray scattering require beam size and divergence compromises. A new microgoniometer enhances micro-diffraction, advancing user-friendly instrumentation for these X-ray techniques.

Area of Science:

  • Structural biology
  • X-ray physics

Background:

  • Third-generation synchrotron radiation sources require compromises in beam size and divergence for protein crystallography micro-diffraction and micro small-angle X-ray scattering.
  • Micro small-angle X-ray scattering (µSAXS) necessitates an angular approach close to the direct beam, limited by sample-position beam divergence.

Purpose of the Study:

  • To develop and assess instrumentation for micro-diffraction and micro small-angle X-ray scattering (µSAXS) at a synchrotron beamline.
  • To explore the complementary development of these techniques.

Main Methods:

  • Utilized a third-generation synchrotron radiation source undulator beamline.
  • Developed a dedicated microgoniometer through an EMBL/ESRF collaboration.
  • Implemented micro-diffraction and micro small-angle X-ray scattering (µSAXS).

Related Experiment Videos

Main Results:

  • Demonstrated the potential of micro-diffraction for protein crystallography.
  • Showcased the complementary development of micro-diffraction and micro small-angle X-ray scattering (µSAXS).
  • Identified beam divergence as a key limitation for micro small-angle X-ray scattering (µSAXS).

Conclusions:

  • The developed microgoniometer is a significant step towards user-friendly instrumentation for micro-diffraction.
  • Optimizing beam characteristics is crucial for advancing micro-diffraction and micro small-angle X-ray scattering (µSAXS) applications.