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Related Experiment Videos

Drug-induced hair colour changes.

J G Bublin1, D F Thompson

  • 1College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City 73117.

Journal of Clinical Pharmacy and Therapeutics
|October 1, 1992
PubMed
Summary

Drug-induced hair color changes are rare but possible. Chloroquine and chemotherapy drugs are most commonly linked, while other medications require more research for confirmed associations.

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Area of Science:

  • Pharmacology
  • Dermatology
  • Toxicology

Background:

  • Hair color changes can be an uncommon adverse effect of medications.
  • Numerous drugs are suspected, but robust evidence is often lacking.

Purpose of the Study:

  • To review the evidence linking various drugs to hair color alterations.
  • To identify medications with confirmed associations and those requiring further investigation.

Main Methods:

  • Literature review of reported cases and studies on drug-induced hair color changes.
  • Analysis of existing data to establish the strength of association for implicated drugs.

Main Results:

  • Chloroquine and cancer chemotherapeutic agents show the strongest evidence for causing hair color changes.
  • Several other drugs, including minoxidil and valproic acid, have potential links but need more supporting data.

Conclusions:

  • Drug-induced hair color changes should be considered in patients with unexplained alterations.
  • Further research is needed to confirm the association for many implicated medications.

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