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Published on: June 29, 2013
[Intrauterine growth curves in a high-income population]
C A Segre1, G M Colletto, J R Bertagnon
1Universidade Federal de São Paulo, SP, Brazil.
Insights
Intrauterine growth curves for newborns at Hospital Albert Einstein (MAE) differed from California curves, particularly at the 90th percentile. Maternal weight gain significantly impacted small-for-gestational age (SGA) and big-for-gestational age (BGA) classifications.
Area of Science:
- Perinatology
- Neonatalogy
- Public Health
Background:
- Intrauterine growth curves are vital for assessing fetal development and predicting neonatal outcomes.
- Characterizing population-specific growth patterns is essential for accurate clinical interpretation.
Purpose of the Study:
- To establish intrauterine growth curves for newborns at Hospital Albert Einstein (MAE).
- To compare MAE newborn growth curves with established curves from California, USA.
- To investigate potential differences in intrauterine growth between the two populations.
Main Methods:
- Birth weight and gestational age data were collected from mothers after 32 weeks of gestation (February 1995 - February 1999).
- Growth curves were plotted, calculating the 10th, 50th, and 90th percentiles for each gestational age.
- MAE curves were statistically compared against California growth curves.
Main Results:
- MAE and California curves showed no significant difference at the 10th and 50th percentiles.
- The 90th percentile MAE curves were lower than those from California.
- The MAE population had fewer small-for-gestational age (SGA) and big-for-gestational age (BGA) newborns compared to California standards.
- Maternal weight gain showed a statistically significant relationship with SGA, normal, and BGA categories for both sexes.
Conclusions:
- Significant differences exist in intrauterine growth patterns between the MAE and California populations.
- Further research is needed to identify specific factors influencing intrauterine growth in the MAE population.
Abstract:
OBJECTIVE: Growth curves can be used to assess intrauterine growth, to predict diseases in newborns, and to characterize different populations. The objective of this study was to obtain intrauterine growth curves of newborns from the maternity ward of the Hospital Albert Einstein (MAE) and compare them with intrauterine growth curves of a population from California, USA. METHODS: We plotted the growth curves according to weight at birth and gestational age, which was obtained according to information from the mother, after the 32nd week of gestation, between February 1995 and February 1999. We calculated the birth weights for the 10th, 50th, and 90th percentiles by each gestational age and compared them with those presented by California growth curves. RESULTS: The growth curves for the 10th and the 50th percentiles did not differ from the California growth curves. For the 90th percentile, however, the MAE growth curves were lower than those of California. The MAE population presented fewer small-for-gestational age (SGA) and big-for-gestational age (BGA) newborns when assessed according to the California curves. The categories of SGA, normal, and BGA for both male and female newborns indicated a statistically significant relation with the weight gain of mothers. CONCLUSIONS: The two populations assessed in this study were different according to intrauterine growth curves. Further studies should be carried out in order to identify specific factors that may be acting on the MAE population.
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