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[Rotavirus detection in feces of children with acute diarrhea]

J V Fernandes1, S M Fonseca, J C Azevedo

  • 1Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.

Jornal De Pediatria
|December 4, 2003
PubMed

Insights

Rotavirus is a significant cause of acute diarrhea in children in Natal, Brazil. Infections are most common in children aged 6-24 months, with peak incidence during the winter months of July, August, and September.

Area of Science:

  • Pediatrics
  • Virology
  • Public Health

Background:

  • Acute diarrhea remains a leading cause of morbidity in children globally.
  • Rotavirus is a primary viral pathogen responsible for severe gastroenteritis in infants and young children.
  • Understanding local prevalence and seasonality is crucial for effective public health interventions.

Purpose of the Study:

  • To determine the prevalence of rotavirus in children with acute diarrhea in Natal, Brazil.
  • To investigate the seasonal distribution of rotavirus infections in this population.
  • To identify age groups most affected by rotavirus-associated diarrhea.

Main Methods:

  • Analysis of fecal samples from 1,903 children aged 1 month to 10 years with acute diarrhea.
  • Detection of rotavirus particles using passive agglutination with anti-rotavirus monoclonal antibodies.
  • Data collected between January 1996 and December 1998 in Natal, RN, Brazil.

Main Results:

  • Rotavirus was detected in 7.9% (151/1,903) of all children studied.
  • Prevalence increased to 12.8% (136/1,065) in children aged 1-24 months.
  • The majority of positive cases (96.3%) were in children aged 6-24 months, with peak incidence from July to September.

Conclusions:

  • Rotavirus plays a significant role in the etiology of acute diarrhea among children in Natal.
  • Infection predominantly affects children within their first two years of life, particularly those aged 6-24 months.
  • A distinct seasonal pattern of rotavirus infection was observed, with higher incidence during the winter months.

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