[Diarrheal disease in hospitalized children - importance of the persistent diarrhea]

M D Lins1, G A Silva

  • 1Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.

Jornal De Pediatria
|December 4, 2003
PubMed

Insights

Persistent diarrhea (PD) is common in hospitalized Brazilian children, especially those under one year old from low-income families. PD significantly increases hospitalization duration and fatal outcomes, highlighting the need for better acute diarrhea management.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Diarrheal diseases remain a leading cause of mortality in young children globally.
  • Persistent diarrhea (PD) is a severe form of diarrhea associated with increased morbidity and mortality.
  • Understanding the epidemiological and clinical characteristics of PD is crucial for effective intervention.

Purpose of the Study:

  • To analyze the epidemiological and clinical patterns of hospitalized children under 24 months with diarrhea.
  • To determine the prevalence of persistent diarrhea (PD) in this population.
  • To identify factors associated with PD and its outcomes.

Main Methods:

  • A cross-sectional study of 300 children hospitalized with diarrhea in Recife, Northeast Brazil (July 1993-March 1994).
  • Data collection included socio-demographic, clinical, and evolutive characteristics.
  • Bidimensional analysis compared acute and persistent diarrhea groups; mortality proportions were compared.

Main Results:

  • The majority of children were under one year old, from low-income families with poor living conditions.
  • High incidence of early weaning (44.2%) and malnutrition (71.1% below 3rd percentile weight).
  • PD occurred in 56.9% of cases, prolonged hospitalization, and was associated with a high fatality rate (72.9%).

Conclusions:

  • Persistent diarrhea is highly prevalent among hospitalized children in this setting, particularly those under one year from disadvantaged backgrounds.
  • PD significantly contributes to prolonged hospital stays and a disproportionately high number of deaths.
  • Inadequate management of acute diarrhea is linked to the progression to persistent diarrhea and adverse outcomes.

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