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Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
The paediatric overview
1Neurology Department, Institute of Child Health, University of Birmingham, Whittall Street, B4 6NH, Birmingham, UK. s.h.green@bham.ac.uk
Insights
Pediatric stroke, encompassing ischemic and hemorrhagic types, is a growing concern. Management requires further research due to complex causes and limited adult stroke data applicability.
Area of Science:
- Pediatric Neurology
- Vascular Neurology
- Pediatric Hematology
Background:
- Stroke in children is an increasingly recognized pediatric illness.
- Causes are multifactorial, rarely attributable to a single factor.
- Sickle cell disease and venous sinus thrombosis are significant contributors.
Purpose of the Study:
- To review the diverse causes of pediatric stroke.
- To highlight key conditions like sickle cell disease and venous sinus thrombosis.
- To emphasize the need for further research in pediatric stroke management.
Main Methods:
- Literature review of pediatric stroke causes and management.
- Analysis of diagnostic and management strategies.
- Emphasis on the role of radiology in diagnosis.
Main Results:
- Pediatric stroke has numerous potential causes, often acting in combination.
- Sickle cell disease and venous sinus thrombosis are prominent etiological factors.
- Radiology is essential for diagnosis and guiding management.
Conclusions:
- Pediatric stroke is a complex condition requiring a comprehensive approach.
- Management strategies cannot always be extrapolated from adult stroke data.
- Further clinical trials are essential to define optimal management and understand natural history.
Abstract:
Stroke in children, both ischaemic and haemorrhagic, is increasingly recognised as an important paediatric illness. This review looks at the wide number of causes, highlighting the fact that often no single factor is causative on its own. There has been an increased recognition worldwide of the importance of sickle cell disease and of the importance of venous sinus thrombosis. Radiology is mandatory in diagnosis and management. Unfortunately, it is not always possible to extrapolate experience from adult stroke in terms of management of these children, and further detailed trials are necessary to understand the natural history, outcome and best forms of management.
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