Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fast 3D imaging using variable-density spiral trajectories with applications to limb perfusion.

Jin Hyung Lee1, Brian A Hargreaves, Bob S Hu

  • 1Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA. ljnhy@mrsrl.stanford.edu

Magnetic Resonance in Medicine
|December 4, 2003
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Left frontal activity measured by fNIRS during a verbal memory task is modulated by predictability in cognitively healthy older adults.

Neuroimage. Reports·2026
Same author

Patterns of Muscle Health in Single- and Multi-Site Chronic Pain: A UK Biobank Normative Modeling Study.

medRxiv : the preprint server for health sciences·2026
Same author

Imaging Near Spinal Fixation Hardware at 0.55 T Compared With 3 T.

Journal of magnetic resonance imaging : JMRI·2026
Same author

Neural Shape Modeling Reveals Early and Progressive Femoral Bone Shape and Cartilage Thickness Changes After Anterior Cruciate Ligament Reconstruction.

medRxiv : the preprint server for health sciences·2026
Same author

Clinical quality of breath-held T1-weighted breast MRI in the supine position.

European journal of radiology·2026
Same author

<i>Formosa sejongensis</i> sp. nov. and <i>Polaromonas potterensis</i> sp. nov., isolated from King George Island, Antarctica.

International journal of systematic and evolutionary microbiology·2026

Ultra-fast 3D imaging is achieved using variable-density k-space sampling with a stack-of-spirals trajectory. This method significantly reduces scan time while maintaining image quality for applications like lower extremity perfusion imaging.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Imaging Physics

Background:

  • Conventional k-space sampling in 3D MRI can be time-consuming.
  • Image data is often concentrated near the k-space origin, with diminishing energy in outer regions.
  • High-spatial-frequency components contribute minimally to overall image energy but require extensive sampling.

Purpose of the Study:

  • To introduce and evaluate a variable-density k-space sampling technique using a stack-of-spirals trajectory for ultra-fast 3D MRI.
  • To reduce scan time in 3D imaging by undersampling outer k-space regions.
  • To assess the impact of this technique on image quality and its applicability to dynamic perfusion imaging.

Main Methods:

  • A novel variable-density stack-of-spirals trajectory was designed to control sampling density in both 2D planes (k(x)-k(y)) and along the k(z) direction.

Related Experiment Videos

  • Spiral trajectories within each k(x)-k(y) plane provided rapid k-space coverage.
  • Phantom studies and application to lower extremity first-pass perfusion imaging were conducted to validate the method.

    • Main Results:

    • Phantom experiments demonstrated that the variable-density stack-of-spirals trajectory preserved reasonable image quality while reducing scan time by approximately 50%.
    • The technique was successfully applied to 3D first-pass perfusion imaging of the lower extremities, achieving a temporal resolution of 2.8 seconds over a large volume.
    • High spatial resolution (2.5 x 2.5 x 8 mm³) was maintained, enabling visualization of the muscle intensity time-course post-contrast injection.

    Conclusions:

    • Variable-density k-space sampling with a stack-of-spirals trajectory is an effective method for ultra-fast 3D MRI.
    • This technique significantly reduces scan time with minimal aliasing artifacts, making it suitable for dynamic imaging applications.
    • The method enables rapid volumetric coverage for perfusion imaging, improving diagnostic capabilities for conditions affecting muscle perfusion.